Practice question

MCQ

Question

Identify which of the following tests is the most convincing to identify a gene as oncogene or tumor suppressor gene.

Options

Choose one · Correct answer highlighted

Transgenic mice overexpressing the candidate oncogene and knock-out mice lacking the candidate tumor suppressor gene Correct Transgenic mice overexpressing the candidate tumor suppressor gene and knock-out mice lacking the candidate oncogene Transgenic mice that overexpresses the candidate oncogene and tumor suppressor gene Knockout mice that lacks the candidate oncogene and tumor suppressor gene

Explanation

Convincing oncogene demonstration requires gain-of-function transgenic mice developing tumors when candidate oncogene overexpressed, while tumor suppressor needs loss-of-function knockout mice developing tumors. Opposite combinations would not show oncogenic phenotype, making transgenic oncogene plus knockout suppressor correct.

Share this question

Discussion

Comments

0 comments

Please log in to join the discussion.

No comments yet. Be the first to start the discussion.

Related blogs

Guides and insights connected to this topic

Biology XII Lab Manual 09 Oct 2026

Experiment 12: Study of Prepared Pedigree Charts of Genetic Traits ( Rolling of tongue, Blood groups, Widow's peak, and Colour blindness.)

AIM To study of prepared pedigree charts of genetic traits such as rolling of tongue, blood groups, widow's peak and colour blindness. PRINCIPLE Pedigree analysis is study of inheritance of traits through family history over generations. Standard symbols are used to represent mal...

Genetic 25 Sep 2026

Genotypic Ratio - Definition, Calculation, Monohybrid Dihybrid Trihybrid Cross, Significance and Important Terms

Understand genotypic ratios, how to calculate them for monohybrid, dihybrid and trihybrid crosses, and why they matter in Mendelian genetics.

25 Sep 2026

Dominant and Recessive Traits - Definition, Homozygous Heterozygous Examples in Plants, Animals and Humans

Learn the difference between dominant and recessive alleles, how homozygous and heterozygous genotypes express traits in plants, animals and humans.