Practice question
Question
A 36-year-old woman reported muscle weakness in the extraocular eye muscles and muscles of the extremities. Her muscle weakness worsens by physical activity and improves with rest. Sensation appears normal. The woman is suffering from?
Explanation
Autoantibodies against nicotinic acetylcholine receptors at neuromuscular junction cause fatigable weakness of ocular and limb muscles worsening with activity and improving with rest, sparing sensation, distinguishing myasthenia gravis from muscular dystrophy or neuropathies.
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