Practice question

Gametogenesis requires combination of mitotic proliferation and meiotic reduction to balance gamete quantity and ploidy. Primordial germ cells and spermatogonial stem cells divide mitotically expanding pool and in males maintaining lifelong production. Subsequent entry into meiosis halves chromosome number via homologous recombination and two sequential divisions, generating genetically diverse haploid spermatids or oocytes. Pure mitosis would retain diploidy incompatible with fertilization restoring diploidy, while meiosis alone without mitotic amplification would insufficiently produce gamete numbers. Dual program ensures both amplification, genetic variability, sustainable fertility across reproductive lifespan and gamete quality.