Practice question

Double-stranded DNA viruses generally package genome as single continuous molecule containing all essential genes on one chromosome, termed monopartite organization. Herpesviruses, poxviruses, adenoviruses and most bacteriophages encode replication, transcription and structural proteins contiguously, ensuring complete genetic information delivered per particle. Segmented dsDNA viruses are exceptionally rare; multipartite organization characteristic of some plant RNA viruses requires multiple particles for infection. Monopartite architecture simplifies replication via theta or strand displacement, allows tight regulation of temporal gene classes and avoids reassortment necessitated by segmentation.