Practice question
Question
Internal transcribed spacer is abbreviated as
Explanation
Within the 45S pre-rRNA, coding regions for mature rRNAs are separated by Internal Transcribed Spacer sequences: ITS1 between 18S and 5.8S, ITS2 between 5.8S and 28S. Unlike NTS, ITS regions are transcribed by Pol I as part of precursor but subsequently excised during maturation by nucleolar processing machineries including RNase MRP and exonucleases like Xrn2 and exosome. Their removal liberates individual rRNAs. Due to rapid evolution and variability, ITS sequences serve as universal DNA barcodes for fungal and plant phylogenetics.
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