Practice question
Question
Cells containing F′ plasmid are
Explanation
Cells containing F' plasmid bear normal haploid chromosome plus extra copy of genes carried on F', creating merodiploid – partial diploid state where those loci are duplicated while rest genome haploid. Term mero means partial, applied by Jacob and Wollman. Merodiploids allow complementation and dominance tests for chromosomal alleles without constructing true diploids impossible in bacteria. For example F' lac+ / lac- mero expresses beta-galactosidase, showing lac+ dominant. Unstable segregation can lose F', reverting to haploid, useful for allelic exchange analysis.
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