Practice question
Question
5' UTR and 3' UTR are part of
Explanation
Eukaryotic messenger RNA architecture comprises 5' 7-methylguanosine cap, 5' untranslated region, central coding region translating into protein, 3' untranslated region, and polyadenosine tail. Both UTRs derived from exonic sequences retained after splicing removal of introns, hence integral parts of mature mRNA post-processing. 5' UTR contains Kozak consensus influencing initiation, while 3' UTR harbors miRNA binding sites and AU-rich elements controlling localization and decay. Rather than DNA or protein segments, UTRs represent regulatory RNA domains modulating translation efficiency and stability, distinguishing mature mRNA from precursor.