Practice question

Traditional view that all enzymes are proteins was challenged by discovery of self-splicing rRNA in Tetrahymena by Cech and RNase P RNA by Altman. These RNAs catalyze phosphodiester bond cleavage and formation, proving catalytic RNA. In RNA world, ribozymes could replicate, process tRNA and synthesize peptides. Modern biology retains ribosomal peptidyl transferase as ribozyme. Understanding catalytic RNA bridges chemical and biological evolution. Hence definition Catalytic RNA molecules captures essential feature linking genotype and phenotype in early life. This concept integrates genetics, ecology and molecular evidence, frequently tested in NEET, GATE and CSIR-NET, highlighting links between