Practice question

Thomas Hunt Morgan chose Drosophila melanogaster for short ten-day generation time, large progeny numbers and easily scorable morphological mutants like white eyes, yellow body and vestigial wings facilitating statistical analysis. At Columbia University laboratory crosses between mutants revealed deviation from Mendelian ratios with excess parental combinations prompting chromosome theory of linkage and inheritance. Student Alfred Sturtevant as undergraduate mapped first X-linked genes calculating distances from recombination frequencies establishing linear gene arrangement confirming Sutton-Boveri hypothesis work earning Morgan Nobel Prize 1933 for chromosome role.