Practice question

Consanguinity describes mating between individuals related by descent from recent common ancestor, such as first cousins or second cousins. Because relatives share alleles identical by descent through common lineage, consanguineous unions substantially increase autozygosity and probability offspring inherits two copies of same rare recessive allele. This elevates incidence of autosomal recessive disorders in children. Random mating and outbreeding denote unrelated partners minimizing identity by descent, while self-fertilization represents extreme inbreeding common in plants. Consanguinity quantified by coefficient of inbreeding F.