Practice question

Reciprocal crosses interchange which sex provides which parental phenotype, e.g., female phenotype A x male phenotype B versus female B x male A. For autosomal inheritance, both sexes carry two copies and transmit alleles equally through meiosis, independent of sex. Consequently F1 and F2 phenotypic distributions remain identical regardless of cross direction. Identical reciprocal results therefore exclude sex-linked inheritance where males inherit X from mother and sex-limited or cytoplasmic patterns involving mitochondrial DNA. Uniformity supports autosomal location with equal biparental transmission.