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Practice question

Question

Autophagy normally functions as

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Explanation

Macroautophagy is a catabolic process in which cytoplasmic material is sequestered in double-membrane autophagosomes that subsequently fuse with lysosomes for degradation. Under nutrient starvation autophagy recycles macromolecules to maintain essential metabolism and is therefore primarily a survival pathway. Only under extreme or prolonged stress does autophagy contribute to cell death.