Practice question

Chronic invasive electroencephalography for presurgical epilepsy mapping and brain-machine interface research requires electrodes that remain electrically stable for weeks inside cortex without corrosion or pronounced glial scarring. Glass micropipettes are excellent for acute intracellular work but mechanically fragile, scalp electrodes with conductive paste are entirely noninvasive, tungsten wires are stiff and suited for acute single-unit recordings but provoke tissue reaction chronically. Nichrome-coated electrodes combine flexibility, strength, biocompatibility and low impedance with durable insulation, enabling reliable subdural and intracortical placement for high-fidelity long-term invasive monitoring of seizure activity.