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Practice question

Question

TLR3 specifically recognizes

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Explanation

TLR3 is an endosomal receptor that recognizes double-stranded RNA, a molecular signature of many viral infections. Signaling proceeds exclusively through the adaptor TRIF, leading to activation of IRF3 and production of type-I interferons. This pathway is critical for antiviral innate immunity in both immune and non-immune cells. Careful