Practice question

Single Nucleotide Polymorphisms arise from single base substitution, insertion or deletion at a defined genomic coordinate. Each SNP represents one locus with typically two alleles, following Mendelian segregation, and heterozygotes display both alleles simultaneously, defining codominance. SNPs are not multilocus like RAPD or AFLP where many loci amplify together, nor dominant where heterozygote cannot be distinguished. They are not repetitive DNA and are usually bi-allelic rather than multiallelic. Their abundance, stability and codominant single-locus nature makes them ideal for association mapping and high-density genotyping.