Practice question
Question
RIG-I-like receptors (RLRs) primarily recognize
Explanation
RIG-I-like receptors are cytosolic sensors of viral RNA. Upon ligand binding they interact with the mitochondrial adaptor MAVS, which then activates TBK1 and IRF3, driving type-I interferon production. This pathway provides a critical intracellular defense against RNA viruses that have escaped endosomal detection by Toll-like receptors. Careful
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