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Which amino acid is not commonly found in an alpha helix?




Which amino acid is not commonly found in an alpha helix?

Correct Answer: (C) Proline

Explanation:

  • Proline: It is called a "helix breaker" because its rigid cyclic structure disrupts the hydrogen bonding and flexibility required for alpha-helix formation.
  • Glutamine: Frequently found in alpha helices due to its side chain's ability to form hydrogen bonds.
  • Arginine: Found in helices, as its positively charged side chain interacts with other residues.
  • Tryptophan: Can stabilize helices due to its bulky, aromatic side chain that participates in hydrophobic interactions.



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