Net gain in Kreb’s cycle (substrate phosphorylation + oxidative phosphorylation)
2ATP + 28 ATP
Net gain of ATP in glycolysis and Kreb’s cycle
Net gain of ATP in glycolysis + Net gain of ATP in Kreb’s cycle
8 ATP + 30 ATP
Over all ATP production by oxidative phosphorylation or ETC
ATP formed by oxidative phosphorylation in glycolysis + ATP formed by oxidative phosphorylation or ETC.
6 ATP + 28 ATP
Difference between Aerobic, Anaerobic Respiration and Fermentation
Molecular oxygen is the ultimate electron acceptor for biological oxidation. The ETS serves to transfer electrons from oxidisable donor to molecular oxygen. The early enzymatic steps involve dehydrogenation whereas the final steps are mediated by a group of enzyme called cytochromes. Ultimately the electrons are transferred to oxygen which is reduced to water. During aerobic respiration ATP is generated by coupled reaction
The ultimate electron acceptor is an inorganic compound other than oxygen. The compounds accepting the hydrogen (electrons) are nitrates, sulphates, carbonates or CO2. Anaerobic respiration produces ATP through phosphorylation reaction involving electron transfer systems. (mechanism not known)
The final electron acceptors are organic compounds. Both electron donors (oxidizable substrate) and electron acceptors (oxidizing agent) are organic compounds and usually both substrates arise from same organic molecules during metabolism. Thus part of the nutrient molecule is oxidised and part reduced and the metabolism results in intramolecular electron rearrangement. ATP is generated by substrate level phosphorylation. This reaction differs from oxidative phosphorylation because oxygen itself is not required for ATP generation.